Patent · US Active

Process of making gyrase and topoisomerase IV inhibitors

US8471014B2 · kind B2 · utility

7Cited by

19References

24Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

Dean Shannon · Milford, US
Tiansheng Wang · Concord, US
Simon Giroux · Cambridge, US

Key dates

Filing date	Jan 13, 2012
Grant date	Jun 25, 2013
Priority date	—
Expiry date	Jan 13, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application is directed to compounds, intermediates and methods for preparing compounds of formula (I)or a pharmaceutically acceptable salts thereof, wherein R is H or F, and each of R3, R4, and R5 are as defined herein. The compounds of formula (I) and pharmaceutical compositions comprising said compounds and salts inhibit bacterial gyrase and/or Topo IV and are useful in treating bacterial infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.