Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide

US8471029B2 · kind B2 · utility

Assignee

• Vertex Pharmaceuticals Incorporated · US

Inventors

• Sneha G. Arekar · Watertown, US
• Steven C. Johnston · Litchfield, US
• Mariusz Krawiec · Marlborough, US
• Ales Medek · Winchester, US
• Praveen Mudunuri · Waltham, US
• Mark Jeffrey Sullivan · Framingham, US

Key dates

• Filing date: Mar 21, 2011
• Grant date: Jun 25, 2013
• Expiry date: Jun 26, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.