Patent · US Active

α-ketoamide derivatives useful endothelial lipase inhibitors

US8476302B2 · kind B2 · utility

0Cited by

1References

17Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Michael N. Greco · Lansdale, US
Margery A. Connelly · Lansdale, US
Shyamali Ghosh · Norristown, US
Dennis J. Hlasta · Doylestown, US
Edward C. Lawson · Pipersville, US
Eric Strobel · Hatboro, US
Michele A. Weidner-Wells · Fryeburg, US
Hong Ye · Lansdale, US

Key dates

Filing date	Sep 26, 2011
Grant date	Jul 2, 2013
Priority date	—
Expiry date	Oct 3, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention is directed to α-ketoamide derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.