Pyrrazolopyridine compounds as dual NK1/NK3 receptor antagonists
US8487102B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Apr 11, 2011 |
| Grant date | Jul 16, 2013 |
| Priority date | — |
| Expiry date | Feb 6, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a compound of formula Iwherein R1, R2, R3, Ar, and n are as defined hereinor to a pharmaceutically active acid addition salt. Compounds of formula I show a high affinity simultaneously to both the NK1 and the NK3 receptors (dual NK1/NK3 receptor antagonists), useful in the treatment of schizophrenia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.