Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
US8501706B2 · kind B2 · utility
15Cited by
3References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 19, 2012 |
| Grant date | Aug 6, 2013 |
| Priority date | — |
| Expiry date | Jul 19, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.