Beta 1,4-galactosyltransferases with altered donor and acceptor specificities, compositions and methods of use
US8512991B2 · kind B2 · utility
1Cited by
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7Claims
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Key dates
| Filing date | Aug 22, 2007 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | Feb 1, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates generally to beta (1,4)-galactosyltransferase I mutants having altered donor and acceptor specificities, and methods of use thereof. In addition, the invention relates to methods for synthesizing oligosaccharides using the beta (1,4)-galactosyltransferase I mutants and to using the beta (1,4)-galactosyltransferase I mutants to conjugate agents, such as therapeutic agents or diagnostic agents, to acceptor molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.