Neprilysin inhibitors
US8513244B2 · kind B2 · utility
76Cited by
24References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 18, 2012 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | May 18, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In one aspect, the invention relates to compounds having the formula:where R1, R2, R3, R4, and R5 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.