Dual-acting benzoimidazole antihypertensive agents
US8513432B2 · kind B2 · utility
1Cited by
27References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 30, 2012 |
| Grant date | Aug 20, 2013 |
| Priority date | — |
| Expiry date | May 30, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds having the formula:wherein Ar, r, n, X, R2, R2′, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and a process and intermediates for preparing such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.