Patent · US Active

Isoxazolo-pyridine derivatives

US8518974B2 · kind B2 · utility

4Cited by

2References

56Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Bernd Buettelmann · Palo Alto, US
Roland Jakob-Roetne · Inzlingen, DE
Henner Knust · Rheinfelden (Baden), DE
Matthew C. Lucas · Sunnyvale, US
Andrew Thomas · Birsfelden, CH

Key dates

Filing date	Feb 10, 2012
Grant date	Aug 27, 2013
Priority date	—
Expiry date	Feb 10, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D491/10
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention is concerned with isoxazole-pyridine derivatives of formula Iwherein X, R1 to R6 are as described herein. The compounds are active on the GABA A α5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.