Patent · US Active

Ethynyl derivatives

US8530472B2 · kind B2 · utility

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13Claims
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Assignee

Inventors

Key dates

Filing dateSep 27, 2012
Grant dateSep 10, 2013
Priority date
Expiry dateSep 27, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/42
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to ethynyl derivatives of formula Iwherein U, V, W, Y, R, R1, R2, R3 and R3′ are as described herein.It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.