Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry
US8541178B2 · kind B2 · utility
6Cited by
3References
30Claims
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Key dates
| Filing date | May 12, 2009 |
| Grant date | Sep 24, 2013 |
| Priority date | — |
| Expiry date | Feb 8, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/94
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods to detect, characterize, and quantitate biological samples after administration of antibody conjugates, antibody-drug conjugates of Formula I, antibodies, and fragments and metabolites thereof, by immunoaffinity bead separation, chromatography, and mass spectrometry are disclosed;Ab-(L-D)p I
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.