Patent · US Active

Anti-CD40 antibodies and methods of inhibiting proliferation of CD40 expressing cells

US8551485B2 · kind B2 · utility

20Cited by
2References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 21, 2009
Grant dateOct 8, 2013
Priority date
Expiry dateSep 6, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/72
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention describes humanized antibodies that target CD40, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the antibodies of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.