Pyrido[3,2-d]pyrimidine PI3K delta inhibitor compounds and methods of use
US8563540B2 · kind B2 · utility
2Cited by
4References
9Claims
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Key dates
| Filing date | Apr 1, 2013 |
| Grant date | Oct 22, 2013 |
| Priority date | — |
| Expiry date | Apr 1, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/107
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Formula I compounds, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting the delta isoform of PI3K, and for treating disorders mediated by lipid kinases such as inflammation, immunological disorders, and cancer. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.