Patent · US Active

JNK modulators

US8569306B2 · kind B2 · utility

2Cited by

0References

14Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Bernd Buettelmann · Palo Alto, US
Bindu Goyal · Fremont, US
Wylie Solang Palmer · Mountain View, US

Key dates

Filing date	Feb 19, 2010
Grant date	Oct 29, 2013
Priority date	—
Expiry date	Mar 10, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of formula (I) modulate JNK wherein X1 and X2 are each simultaneously N or CH; X3 is CH—R2 Or N—SO2R, where R is lower alkyl; R1 is aryl or heteroaryl, substituted with 0-3 lower alkyl radicals; R2 is (II), where R3 is H, lower acyl, or an amino acid, or a pharmaceutically acceptable salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.