Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them

US8580842B2 · kind B2 · utility

Assignee

• Abbott GmbH & Co. KG · DE

Inventors

• Wilfried Lubisch · Mannheim, DE
• Wilfried Hornberger · Wiesbaden, DE
• Thorsten Oost · Biberach an der Riß, DE
• Daryl Sauer · Pleasant Prairie, US
• Liliane Unger · Ludwigshafen, DE
• Wolfgang Wernet · Ludwigshafen, DE
• Hervé Geneste · Schifferstadt, DE

Key dates

• Filing date: Jul 20, 2010
• Grant date: Nov 12, 2013
• Expiry date: Sep 6, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5, R6, and R7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.