Patent · US Active

Antifungal compositions with improved bioavailability

US8591948B2 · kind B2 · utility

0Cited by

6References

41Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Lieven Elvire Colette Baert · Brugge, BE
Geert Verreck · Beerse, BE
Dany Thone · Beerse, BE

Key dates

Filing date	Jun 1, 2006
Grant date	Nov 26, 2013
Priority date	—
Expiry date	Jan 28, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P31/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.