Cycloalkyl-fused tetrahydroquinolines as CRTH2 receptor modulators
US8592383B2 · kind B2 · utility
4Cited by
4References
48Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 14, 2012 |
| Grant date | Nov 26, 2013 |
| Priority date | — |
| Expiry date | Jun 14, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I),and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.