Drug loaded polymeric nanoparticles and methods of making and using same

US8603534B2 · kind B2 · utility

Assignee

• BIND Therapeutics, Inc. · US

Inventors

• Stephen E. Zale · Hopkinton, US
• Greg Troiano · Pembroke, US
• Mir Mukkaram Ali · Woburn, US
• Jeff Hrkach · Lexington, US
• James Wright · Lompoc, US

Key dates

• Filing date: May 28, 2013
• Grant date: Dec 10, 2013
• Expiry date: May 28, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S977/773
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic)acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.