Composition for repression of hyperlipidemia and obesity through suppression of intestinal cholesterol absorption
US8609098B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Apr 25, 2011 |
| Grant date | Dec 17, 2013 |
| Priority date | — |
| Expiry date | Apr 25, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are a composition for inhibiting hyperlipidemia and obesity through suppression of intestinal cholesterol absorption. An IgY-type antibody derived from yolk to NPC1L1 (Niemann-Pick C1-Like1), contained, as an active ingredient, in the composition of the present invention is linked to NPC1L1 (Niemann-Pick C1-Like1) that is a cholesterol transport protein in the intestines, thus interfering with binding between cholesterol and the transport protein to completely block absorption of cholesterol in the body and thereby prevent hyperlipidemia and obesity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.