Patent · US Active

Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof

US8629173B2 · kind B2 · utility

10Cited by

56References

39Claims

0Family size

Assignee

CELGENE CORPORATION · US

Inventors

George W. Muller · Northbrook, US
Peter Schafer · Ottersheim, DE
Hon-Wah Man · Princeton, US
Chuansheng Ge · Montgomery, US
Jean Xu · Hackettstown, US

Key dates

Filing date	Nov 18, 2011
Grant date	Jan 14, 2014
Priority date	—
Expiry date	Nov 18, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.