Piperidine/piperazine derivatives

US8633197B2 · kind B2 · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Jean-Pierre Andre Marc Bongartz · Turnhout, BE
• Guy Rosalia Eugeen Van Lommen · Berlaar, BE
• Erwin Coesemans · Nijlen, BE
• Christophe Francis Robert Nestor Buyck · Temse, BE

Key dates

• Filing date: Jun 5, 2008
• Grant date: Jan 21, 2014
• Expiry date: Jan 15, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D231/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a DGAT inhibitor of formulaincluding any stereochemically isomeric form thereof, a N-oxide thereof, a pharmaceutically acceptable salt thereof or a solvate thereof, and methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use as a medicine of said compounds.