Eukaryotic cell display systems
US8637435B2 · kind B2 · utility
0Cited by
34References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2008 |
| Grant date | Jan 28, 2014 |
| Priority date | — |
| Expiry date | Jan 16, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides expression vectors and helper display vectors which can be used in various combinations as vector sets for display of polypeptides on the outer surface of eukaryotic host cells. The expression vector of the invention can be used alone for soluble expression without having to change or reengineer the display vectors. The display systems of the invention are particularly useful for displaying a genetically diverse repertoire or library of polypeptides on the surface of yeast cells, and mammalian cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.