Patent · US Active

Bicyclic compounds as inhibitors of diacylglycerol acyltransferase

US8637507B2 · kind B2 · utility

30Cited by
5References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 16, 2010
Grant dateJan 28, 2014
Priority date
Expiry dateSep 28, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to novel heterocyclic compounds as diacylglycerol acyltransferase (“DGAT”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose. An illustrative compound of the invention is shown below: formula (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.