Compositions useful as inhibitors of protein kinases
US8642779B2 · kind B2 · utility
0Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 9, 2009 |
| Grant date | Feb 4, 2014 |
| Priority date | — |
| Expiry date | Dec 24, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula I:or a pharmaceutically acceptable derivative thereof, wherein A, B, Q, R1, and R2 are as described in the specification. These compounds are inhibitors of protein kinase, particularly inhibitors of AKT or PDK1 kinase, mammalian protein kinases involved in proliferative and neurodegenerative disorders. The invention also provides pharmaceutical compositions comprising the compounds of the invention, processes for preparing the compounds, and methods of utilizing those compositions in the treatment of various disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.