Patent · US Active

Alkyl amines improve detection of components of formaldehyde-fixed biological samples

US8652775B2 · kind B2 · utility

1Cited by

2References

5Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Stephen G. Will · Oakland, US
Veeraiah Bodepudi · San Ramon, US
Ellen H. Fiss · Albany, US
Rachel Shahinian · Alameda, US

Key dates

Filing date	Mar 28, 2008
Grant date	Feb 18, 2014
Priority date	—
Expiry date	Aug 13, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6806
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Alkyl amines act to release formaldehyde cross-linking that occurs in biological samples. Thus, contacting alkyl amines to formaldehyde fixed samples is a useful way to render biological components of the samples, including nucleic acids or proteins, more accessible to detection and characterization.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.