Method for the analysis of ovarian cancer disorders
US8652777B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 16, 2008 |
| Grant date | Feb 18, 2014 |
| Priority date | — |
| Expiry date | Nov 6, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a method for the analysis of ovarian cancer disorders, comprising determining the genomic methylation status of one or more CpG dinucleotides in a sequence selected from the group of sequences according to SEQ ID NO. 1 to 10 and/or SEQ ID NO. 50 to SEQ ID NO. 60. Optionally, additionally following steps are performed, the one or more results from the methylation status test is input into a classifier that is obtained from a Diagnostic Multi Variate Model, calculating a likelihood as to whether the sample is from a normal tissue or an ovarian cancer tissue and/or, calculating an associated p-value for the confidence in the prediction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.