Reflective diffractometric hydrogel sensor for biological and chemical detection

US8663563B2 · kind B2 · utility

Assignees

• Purdue Research Foundation · US
• The Board of Regents of the University of Texas System · US

Inventors

• Cagri A. Savran · West Lafayette, US
• Chun-Li Chang · West Lafayette, US
• Zhenwen Ding · Santa Clara, US
• Babak Ziaie · West Lafayette, US
• Andrew Ellington · Austin, US
• Venkata Naga Lakshmi Rekha Patchigolla · Columbus, US

Key dates

• Filing date: Dec 5, 2011
• Grant date: Mar 4, 2014
• Expiry date: Sep 4, 2032

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B82Y35/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A reflective diffractometric hydrogel sensor includes an upper layer, including a microfluidic chamber formed from a substantially transparent material and configured to contain a solution, a reflective diffraction grating positioned within the microfluidic chamber, the diffraction grating including a plurality of hydrogel strips configured to change in dimension in response to a stimulus, each hydrogel strip having a top surface coated with a reflective material and a bottom surface in contact with the upper layer substrate, and a reflective surface below the reflective diffraction grating wherein when a coherent light is incident upon and reflected from the upper layer at an angle substantially normal to the upper layer an interference diffraction pattern results, including a first diffraction mode, a light intensity of which indicates the relative distance between the top surfaces of the plurality of hydrogel strips and the reflective surface.