Patent · US Active

Substituted heterocyclic compounds as ion channel modulators

US8664399B2 · kind B2 · utility

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2Claims
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Assignee

Inventors

Key dates

Filing dateDec 6, 2012
Grant dateMar 4, 2014
Priority date
Expiry dateDec 6, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to sodium channel inhibitors of Formula (I):in which R1, R2, R3, R4, R5, X, Y, and Z are as defined herein, and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes.The invention also relates to methods for the preparation of the compounds, and to pharmaceutical compositions containing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.