Binding polypeptides with diversified and consensus VH/VL hypervariable sequences
US8679490B2 · kind B2 · utility
27Cited by
111References
49Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 7, 2006 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Nov 7, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/56
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides variant hypervariable regions comprising selected amino acid sequence diversity. Libraries comprising a plurality of these polypeptides are also provided. In addition, methods of and compositions for generating and using these polypeptides and libraries are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.