Piperazinylpiperidine derivatives as chemokine receptor antagonists
US8680104B2 · kind B2 · utility
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10References
9Claims
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Key dates
| Filing date | Aug 1, 2012 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Aug 1, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of Formula I:wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR5. The compounds can be used, for example, to treat diseases associated with chemokine receptor expression or activity such as inflammatory diseases, immune diseases and viral infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.