Inhibitors of AKT activity
US8691825B2 · kind B2 · utility
3Cited by
1References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 29, 2010 |
| Grant date | Apr 8, 2014 |
| Priority date | — |
| Expiry date | Jun 9, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention provides for substituted fused pyrimidine compounds of Formula A that inhibit Akt activity:In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.