Bispecific anti-VEGF/anti-ANG-2 antibodies

US8703130B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Monika Baehner · Munich, DE
• Ulrich Brinkmann · Weilheim, DE
• Guy Georges · Habach, DE
• Remko Albert Griep · Slemmestad, NO
• Sabine Imhof-Jung · Planegg, DE
• Anita Kavlie · Oslo, NO
• Hubert Kettenberger · Munich, DE
• Christian Klein · Iffeldorf, DE
• Joerg Thomas Regula · Munich, DE
• Wolfgang Schaefer · Sankt Augustin, DE
• Juergen Michael Schanzer · Traunstein, DE
• Werner Scheuer · Penzberg, DE
• Stefan Seeber · Penzberg, DE
• Markus Thomas · Rheinfelden (Baden), DE

Key dates

• Filing date: Aug 9, 2012
• Grant date: Apr 22, 2014
• Expiry date: Aug 9, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.