Patent · US Active

Antibody variants

US8703133B2 · kind B2 · utility

4Cited by

3References

2Claims

0Family size

Assignee

Genentech, Inc. · US

Inventors

Yvonne Chen · San Mateo, US
Henry B. Lowman · El Granada, US
Yves Muller · Panketal, DE

Key dates

Filing date	Mar 21, 2011
Grant date	Apr 22, 2014
Priority date	—
Expiry date	Mar 21, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antibody variants of parent antibodies are disclosed which have one or more amino acids inserted in a hypervariable region of the parent antibody and a binding affinity for a target antigen which is at least about two fold stronger than the binding affinity of the parent antibody for the antigen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.