Patent · US Active

Fused heterocyclic compounds as ion channel modulators

US8703759B2 · kind B2 · utility

7Cited by
24References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 30, 2011
Grant dateApr 22, 2014
Priority date
Expiry dateFeb 13, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I:wherein R1, R2, R3, R4, and R5 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.