Immunological uses of immunomodulatory compounds for vaccine and anti-infectious disease therapy

US8715677B2 · kind B2 · utility

Assignee

• CELGENE CORPORATION · US

Inventors

• Justin Blake Bartlett · Berkeley Heights, US
• George W. Muller · Northbrook, US
• Peter Schafer · Ottersheim, DE
• Christine Galustian · Croydon, GB
• Angus Dalgleish · London, GB
• Brendan Meyer · London, GB

Key dates

• Filing date: Aug 31, 2006
• Grant date: May 6, 2014
• Expiry date: Aug 14, 2028

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods of enhancing immune response to an immunogen in a subject are disclosed. Also disclosed are methods of reducing the sensitivity to an allergen in a subject. The methods comprise the administration of an immunomodulatory compound in specific dosing regimens that result in enhanced immune response or reduced sensitivity.