Protein kinase inhibitors and use thereof

US8735584B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Bayard R. Huck · Sudbury, US
• Xiaoling Chen · Sharon, US
• Lizbeth Celeste Deselm · Melrose, US
• Christopher Charles Victor Jones · Arlington, US
• Srinivasa Karra · Pembroke, US
• Yufang Xiao · Lexington, US
• Andreas Goutopoulos · Boston, US
• Amanda E. Sutton · Hingham, US

Key dates

• Filing date: Feb 25, 2009
• Grant date: May 27, 2014
• Expiry date: Dec 23, 2029

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are benzonaphthyridinyl derivative compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to kinase signal transduction inhibition, regulation or modulation.