Methods for characterizing agonists and partial agonists of target molecules
US8744778B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Aug 12, 2011 |
| Grant date | Jun 3, 2014 |
| Priority date | — |
| Expiry date | Nov 23, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.