Substituted piperazino-dihydrothienopyrimidines

US8754073B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Pascale Pouzet · Biberach, DE
• Ralf Anderskewitz · Laupheim, DE
• Horst Dollinger · Schemmerhofen, DE
• Dennis Fiegen · Biberach an der Riß, DE
• Thomas Fox · Biberach, DE
• Rolf Goeggel · Ulm, DE
• Christoph Hoenke · Ingelheim am Rhein, DE
• Domnic Martyres · Biberach, DE
• Peter Nickolaus · Warthausen, DE
• Klaus Klinder · Oggelshausen, DE

Key dates

• Filing date: Oct 16, 2008
• Grant date: Jun 17, 2014
• Expiry date: Nov 26, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Piperidinodihydrothienopyrimidines of formula 1wherein X is SO or SO2 (preferably SO), and R1, R2, R3, and R4 may have the meanings given in the disclosure and claims, pharmacologically acceptable salts thereof, and pharmaceutical compositions containing these compounds. These piperidinodihydrothienopyrimidines are suitable for the treatment of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system, or cancers.