Patent · US Active

Co-crystals and pharmaceutical compositions comprising the same

US8759353B2 · kind B2 · utility

0Cited by

98References

32Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

Patrick R. Connelly · Harvard, US
Irina Nikolaevna Kadiyala · Newton, US
Kathy Stavropoulos · Quincy, US
Yuegang Zhang · Wayland, US
Steven C. Johnston · Litchfield, US
Govinda Rao Bhisetti · Lexington, US
Valdas Jurkauskas · Cambridge, US
Peter Jamison Rose · Littleton, US

Key dates

Filing date	Feb 27, 2008
Grant date	Jun 24, 2014
Priority date	—
Expiry date	Oct 24, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthranilic acid, and d-Biotin. Also within the scope of this invention are methods of making and using the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.