Patent · US Active

Monocyclic CGRP receptor antagonists

US8765759B2 · kind B2 · utility

0Cited by
3References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 24, 2009
Grant dateJul 1, 2014
Priority date
Expiry dateJun 12, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is directed to compounds of the formula:(wherein variables A1, A2, A3, G1, G2, G3, G4, J, Ea, Eb, Ec, R6, R7, and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.