Ring-fused 4-aminopyrimidines and use thereof as stimulators of soluable guanylate cyclases

US8765769B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Markus Follmann
• Johannes-Peter Stasch · Wuppertal, DE
• Gorden Redlich · Bochum, DE
• Jens Ackerstaff · Mülheim an der Ruhr, DE
• Nils Griebenow · Milford, US
• Andreas Knorr · Erkrath, DE
• Frank Wunder · Wuppertal, DE
• Volkhart Min-Jian Li · Velbert, DE

Key dates

• Filing date: Jul 5, 2011
• Grant date: Jul 1, 2014
• Expiry date: Jul 5, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel fused 4-aminopyrimidines, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.