Alkylamine-substituted dicyanopyridine and amino acid ester prodrugs thereof

US8772498B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Alexandros Vakalopoulos · Hilden, DE
• Daniel Meibom · Leverkusen, DE
• Barbara Albrecht-Küpper · Uerdingen, DE
• Katja Zimmermann · Mülheim an der Ruhr, DE
• Jörg Keldenich · Wuppertal, DE
• Hans-Georg Lerchen · Leverkusen, DE
• Peter Nell · Wuppertal, DE
• Frank Süβmeier · Birkenfeld, DE
• Ursula Krenz · Leichlingen, DE

Key dates

• Filing date: Mar 13, 2013
• Grant date: Jul 8, 2014
• Expiry date: Mar 13, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K5/06165
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 6-alkylamino-substituted dicyanopyridines, to their amino acid ester prodrugs, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular disorders.