Patent · US Active

PDE10 modulators

US8772510B2 · kind B2 · utility

0Cited by

0References

25Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Stephan Bachmann · Allschwil, CH
Alexander Flohr · Basel, CH
Katrin Groebke Zbinden · Liestal, CH
Matthias Koerner · Antdorf, DE
Bernd Kuhn · Sursee, CH
Jens-Uwe Peters · Weil am Rhein, DE
Markus Rudolph · Basel, CH

Key dates

Filing date	Aug 30, 2012
Grant date	Jul 8, 2014
Priority date	—
Expiry date	Aug 30, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula (I)wherein R1, R2, R3, R5, W, X, X1, Y, Y1, Z and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used in the treatment of CNS disorders such as schizophrenia, Alzheimer's disease, and Parkinson's disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.