Pyrazole compounds as CRTH2 antagonists

US8791272B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Thorsten Oost · Biberach an der Riß, DE
• Ralf Anderskewitz · Laupheim, DE
• Dieter Hamprecht · Verona, IT
• Christoph Hoenke · Ingelheim am Rhein, DE
• Domnic Martyres · Biberach, DE
• Wolfgang Rist · Ingelheim am Rhein, DE
• Peter Seither · Biberach an der Riß, DE

Key dates

• Filing date: Jan 24, 2011
• Grant date: Jul 29, 2014
• Expiry date: Jul 14, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to pyrazole compounds of formula (I) and pharmaceutically acceptable salts thereof having CRTH2-activity,wherein W, L1, L2, X, L3, Y, R1 and R2 are as defined in the specification and claims, to their use as medicaments and to pharmaceutical formulations, containing said compounds or containing a combination of said compounds with one or more active substances.