3-Methyl-imidazo[1,2-b]pyridazine derivatives

US8822468B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Pascal Furet · Basel, CH
• Clive McCarthy · Woodstock, GB
• Joseph Schoepfer · Riehen, CH
• Carsten Spanka · Bad Kötzting, DE
• Melanie Stang · Basel, CH
• Frederic Stauffer · Hésingue, FR

Key dates

• Filing date: Mar 2, 2009
• Grant date: Sep 2, 2014
• Expiry date: Apr 7, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of formula (I) and salts thereofwherein the substituents are as defined in the specification, the application of a compound of formula (I) in a process for the treatment of the human or animal body, in particular with regard to C-Met tyrosine kinase mediated disease; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner; processes for the preparation of a compound of formula (I).