Patent · US Active

Pyrimidyl cyclopentanes as AKT protein kinase inhibitors

US8846681B2 · kind B2 · utility

10Cited by
30References
91Claims
0Family size

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Key dates

Filing dateJun 14, 2011
Grant dateSep 30, 2014
Priority date
Expiry dateJan 4, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof.Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.