Patent · US Active

Multiwell assay apparatus and method for determining biological activity of compounds

US8852881B2 · kind B2 · utility

0Cited by
9References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 29, 2006
Grant dateOct 7, 2014
Priority date
Expiry dateApr 7, 2032

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L2300/0829
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A device for characterizing the biological properties of cells can include a plurality of dual-compartment assay chambers wherein the compartments of each chamber are separated by a cell layer across which ions can flow. The biological properties of the cell layer in the presence or absence of experimental compounds can be determined by measuring an electrical gradient across the layer. A individual dual-compartment chamber of this type may be referred to as an “Ussing chamber.”

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.