Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes
US8858931B2 · kind B2 · utility
5Cited by
1References
15Claims
0Family size
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Key dates
| Filing date | Jul 31, 2006 |
| Grant date | Oct 14, 2014 |
| Priority date | — |
| Expiry date | Nov 20, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/572
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the field of anticancer therapy, and to the identification of immunogenic peptides derived from the human telomerase reverse transcriptase (hTERT). The present invention relates to polynucleotides encoding hTERT epitopes restricted to MHC class I molecule, analogs thereof and polyepitopes containing such epitopes and/or analogs. Are also included in the present invention, vector and cell comprising such polynucleotides. The present invention also concerns composition comprising hTERT polypeptides, corresponding polynucleotides, vectors and cells, for use in the treatment and/or prevention of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.