Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer'S disease
US8865701B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Feb 20, 2010 |
| Grant date | Oct 21, 2014 |
| Priority date | — |
| Expiry date | Feb 28, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to spiropyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.