Recombinant host cells comprising phosphoketolases
US8871488B2 · kind B2 · utility
35Cited by
5References
48Claims
0Family size
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Key dates
| Filing date | Jun 15, 2011 |
| Grant date | Oct 28, 2014 |
| Priority date | — |
| Expiry date | Oct 9, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is related to recombinant host cells comprising: (i) at least one deletion, mutation, and/or substitution in an endogenous gene encoding a polypeptide that converts pyruvate to acetaldehyde, acetyl-phosphate or acetyl-CoA; and (ii) a heterologous polynucleotide encoding a polypeptide having phosphoketolase activity. The present invention is also related to recombinant host cells further comprising (iii) a heterologous polynucleotide encoding a polypeptide having phosphotransacetylase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.